What is Hyrdocephalus

Hydrocephalus is one of the most common congenital (present at birth) problems in children and the most common clinical problem pediatric neurosurgeons face. It happens to one child per 1,000 live births and is a major social, medical and economic problem.

Cerebrospinal fluid is important to the human body, making hydrocephalus research a priority. CSF bathes and cushions the brain and quickly transfers signals between its different areas. If CSF proteins change during different stages of hydrocephalus, it may harm brain development and a child’s chances of survival. A child with hydrocephalus has too much CSF inside the ventricles of the brain. The treatment for hydrocephalus—the shunt—has saved many lives. However, we still don’t have a cure.

Hydrocephalus is almost always a life-long condition, and shunting is not a perfect treatment. Up to 15 percent of children with shunts have painful problems during their lifetime—problems like infections or shunts that don’t work properly. This often means operating many times on a child to replace the shunt. Dr. Avellino and his colleagues would like to save children from this pain.

At Children’s, we’re asking, “How can we treat patients in a less invasive manner and possibly cure hydrocephalus?”

This content is from Dr. Avellino's research, and has been provided by Children's Hospital & Regional Medical Center Neurosurgery website.

Facts:

• 1 million people have hydrocephalus in the US.
• There are 180 different causes.
• There is no cure and very little research. The NIH funds 60 cents per person with hydrocephalus per year yet $300 per person per year with Juvenile Diabetes and the prevalence of 1 million is the same for each disease.
• The standard treatment, a shunt, developed in 1952 has a 50% failure rate after just two years which is the reason so many have to have multiple brain surgeries just to stay alive.
• 60% of children with hydrocephalus are not independent as adults and require assistance.
• 50% of children with hydrocephalus score 80 or below on standardized intelligence tests.
• It costs the US $1 billion per year in health care costs to treat hydrocephalus.